Royal Air Force Typhoon FGR4s have operated alongside French aircraft in a joint strike on an underground arms cache in Syrian territory used by the Islamic State group (IS), according to the UK Ministry of Defence.
The location, pinpointed through reconnaissance, was thought to be housing weapons and explosive materials, the statement said, and was located in hills just north of the historic site of Palmyra in Syria's central region.
"Our fighter planes utilized Paveway IV guided bombs to hit a several entry passages providing entry to the depot... initial indications indicate the target was engaged successfully," the ministry announced.
There was no indication of any harm to civilians in the strike on Saturday evening and every plane involved made a safe return, the MoD added.
The Typhoon fighters were assisted by a Voyager refuelling tanker.
Daesh - alternatively referred to as the so-called Islamic State - established jihadist rule over significant areas in Iraq and Syria before its territorial defeat in 2019.
"This strike demonstrates the UK's leading role, and commitment to operate in unison with our allies, to eliminate any revival of Daesh and their violent and radical beliefs in the Middle East," the British Defence Secretary the Defence Secretary stated.
RAF aircraft have conducted surveillance missions over Syrian airspace to "forestall any attempted resurgence" of the group subsequent to its defeat at the climactic battle in Baghuz in the year 2019, the MoD reported.
"I extend gratitude to all the members of British forces who took part in this operation for their professionalism and their valour," Healey added. "They were among a great many UK service members stationed over the festive period. This operation, to remove dangerous terrorists who endanger our way of life, highlights how our armed forces are ready to step up, all year round, keeping Britain secure at home and powerful internationally."
During December, the United States armed forces conducted what it described as a "major assault" targeting Daesh sites in Syria, after an attack resulted in the deaths of two American soldiers and a civilian linguist in Palmyra.
The UN says Islamic State still boasts an estimated 5,000 to 7,000 combatants in Iraq and Syria.